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Judith S Bond Selected Research

Tiopronin (Thiola)

3/2014Meprin metalloproteases inactivate interleukin 6.
2/2013Post-transcriptional regulation of meprin α by the RNA-binding proteins Hu antigen R (HuR) and tristetraprolin (TTP).
2/2011Balance of meprin A and B in mice affects the progression of experimental inflammatory bowel disease.
3/2009Disruption of the meprin alpha and beta genes in mice alters homeostasis of monocytes and natural killer cells.
1/2009Meprin A metalloproteases enhance renal damage and bladder inflammation after LPS challenge.
11/2008Prointerleukin-18 is activated by meprin beta in vitro and in vivo in intestinal inflammation.
3/2008Targeted disruption of the meprin metalloproteinase beta gene protects against renal ischemia-reperfusion injury in mice.
11/2007Human and mouse homo-oligomeric meprin A metalloendopeptidase: substrate and inhibitor specificities.
10/2005Meprin beta metalloprotease gene polymorphisms associated with diabetic nephropathy in the Pima Indians.
10/2005Meprin-alpha in chronic diabetic nephropathy: interaction with the renin-angiotensin axis.
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Judith S Bond Research Topics

Disease

10Inflammation (Inflammations)
03/2014 - 01/2003
6Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
03/2014 - 11/2007
5Neoplasms (Cancer)
06/2005 - 01/2003
4Diabetic Nephropathies (Diabetic Nephropathy)
11/2007 - 02/2003
2Ischemia
10/2011 - 03/2008
2Acute Kidney Injury (Acute Renal Failure)
01/2009 - 06/2005
2Urinary Tract Infections (Urinary Tract Infection)
01/2009 - 06/2005
2Neoplasm Metastasis (Metastasis)
06/2005 - 01/2005
2Infections
06/2005 - 01/2003
2Breast Neoplasms (Breast Cancer)
01/2005 - 01/2005
1Cystic Fibrosis (Mucoviscidosis)
08/2014
1Alzheimer Disease (Alzheimer's Disease)
08/2011
1Colitis
02/2011
1Edema (Dropsy)
01/2009
1Reperfusion Injury
03/2008
1Kidney Diseases (Kidney Disease)
10/2005
1Birth Weight (Birth Weights)
02/2003

Drug/Important Bio-Agent (IBA)

14Tiopronin (Thiola)FDA Link
03/2014 - 02/2003
14Metalloproteases (Metalloproteinases)IBA
03/2014 - 01/2003
4meprin AIBA
09/2013 - 01/2003
3CytokinesIBA
03/2014 - 04/2005
3Peptide Hydrolases (Proteases)FDA Link
02/2013 - 01/2003
2Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA
01/2005 - 01/2005
2EnzymesIBA
01/2005 - 01/2003
2Hormones (Hormone)IBA
01/2005 - 01/2005
2PolyaminesIBA
01/2005 - 01/2005
2Eflornithine (Ornidyl)FDA Link
01/2005 - 01/2005
1Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA
08/2014
1Interleukin-6 (Interleukin 6)IBA
03/2014
1OccludinIBA
09/2013
1villinIBA
10/2011
1Membrane Proteins (Integral Membrane Proteins)IBA
08/2011
1meprin BIBA
02/2011
1Nitric Oxide (Nitrogen Monoxide)FDA Link
02/2011
1Dextran SulfateIBA
02/2011
1Interleukin-18 (Interleukin 18)IBA
11/2008
1Protein Isoforms (Isoforms)IBA
03/2008
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
10/2005
1Proteins (Proteins, Gene)FDA Link
10/2005
1ReninIBA
10/2005
1AngiotensinsIBA
10/2005
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
04/2005
1Peptides (Polypeptides)IBA
04/2005
1Extracellular Matrix ProteinsIBA
04/2005
1Green Fluorescent ProteinsIBA
01/2005
1OrnithineIBA
01/2005
1PutrescineIBA
01/2005
1ZincIBA
02/2003

Therapy/Procedure

1Oral Administration
02/2011
1Intraperitoneal Injections
03/2009
1Therapeutics
10/2005
1Drug Therapy (Chemotherapy)
01/2005
1Treatment Delay
01/2005
1Intravenous Injections
01/2005